The Utah Procurement Code provides that a procurement may be made without competition when the University determines that there is only one source that can reasonably meet the University’s need for the required supply or service, as described in Utah Code Ann. § 63G-6a-802.

The Purchasing Department has received the following request for sole source procurement

Product and/or Service to be purchased: VT-iSIM

Sole Source Supplier: Biovision Technologies Inc.

Earliest Proposed Purchase Date: March 19, 2024

Buyer Name: Anthony Ferrara

Sole Source Justification:

The VT-iSIM from VisiTech is new, integrated technology that allows for high-speed super-resolution imaging of live specimens. This is defined as 100 fps with a spacial resolution of 100 nm in X,Y dimensions and 280 nm in Z dimension. The VT-iSIM can produce super-res images in real-time in multiple wavelengths of detection. Additionally, this method of super-res does not need specialized fluorophores. Thus, we can utilize a wide range of strains and reagents we’ve already made using common fluorophores such as GFP and mCherry. We will be able to image subcellular processes and mechanisms such as vesicular transport of proteins in living cells with enhanced resolution and sensitivity not available via other methods. BioVision Technologies is the only authorized distributor in the United States.

The VT-iSIM is a unique combination of imaging capabilities. While there are several systems available from other venders, none of them provide this constellation of technologies. Discussion with the University of Utah Cell Imaging Core compared the uniqueness of this instrumentation. For example, the VT-iSIM and the Live SR (Super Resolution Spinning Disk – Gataca Systems) use similar structured illumination to achieve super-resolution, but the Live-SR does not have equivalent temporal resolution. Also, the Yokogawa CSU-X1 Confocal Scanner Unit can achieve similar frames per second, but lacks the super-resolution. Importantly, the quoted VT-iSIM also integrates FRAP, bright field, six laser lines (wavelengths), and dual cameras for simultaneous multi-channel acquisition on our existing Nikon Ti2 inverted microscope platform.